Blood Case Studies

In this section, you will apply your understanding of blood components and CBC results to analyze real clinical scenarios. Use Reference Tables 1–3 in the “Blood Analysis” section to help interpret the results for each patient.

Each case study will include:

• Patient symptoms 

• A complete blood count (CBC) 

• A white blood cell differential 

• A blood smear image

You will use this information to identify patterns and determine the most likely diagnosis of each case.

Your Task

For each case study, you will:

1. Examine the Data

  • Review the CBC results carefully
  • Compare values to Table 3 – Reference Values
  • Identify any values that are increased or decreased

2. Analyze the White Blood Cells

  • Use Table 2 – White Blood Cell Differential
  • Identify which white blood cell types are elevated or reduced
  • Consider what these changes might indicate

3. Interpret the Blood Smear

  • Observe the types and appearance of cells
  • Determine whether cells are:
    • mostly mature
    • mostly immature
    • a mixture of stages

4. Identify Patterns

  • Use your knowledge of:
    • Table 1 – CBC Components
    • cell function
    • disease characteristics

Ask yourself:

• Are white blood cells numbers altered?

• Are immature cells present?

• Is there a mix of cell stages?

• Are red blood cells or platelets affected?


5. Determine the Diagnosis

  • Select the most likely diagnosis from the options provided
  • Support your answer using evidence from:
    • CBC results
    • differential
    • smear observations

6. Answer the Guiding Questions

  • Explain your reasoning clearly
  • Connect your answers to:
    • cell function
    • blood cell development
    • disease processes

Tip: Focus on patterns, not just individual numbers. Diseases often affect multiple components of the blood, and recognizing these patterns will help you make accurate diagnoses.